based on the solo gaming sheets from, Perplexing Ruins.
[...] so pick a game system to run - i recommend something rules lite (Cairn, my game Ward, Bastards. are good choices) roll up 1-3 characters. roll up a home town and put it in the center hex. then roll up a magical item "you need to retrieve" using the tables. decided how many hexes away is the "objective" (roll 1d6 then 1d4 to determine direction and distance) - travel to that hex, using the procedures described on the sheet. Enter a dungeon. use the dungeon sheet to create the dungeon, in which you can find the quest item. return it to town. Congrats solo adventure #1 complete (albeit very simple)
HD for creatures = 1d6 each.
Keep it simple at first. treat it like an video game rpg, so after first quest done, include an NPC to give you your next quest. This time, roll it up on the quest generator tables. then run with it!
hope this helps a little