akhileshkaushal / infinityFlow

Infinity Flow: High-throughput single-cell quantification of 100s of proteins using conventional flow cytometry and machine learning

This repository contains the software package infinityFlow designed to analyze massively-parallel cytometry experiments, such as BioLegend's LEGENDScreen or's BD Cell surface screening panels.

You can learn more about the Infinity Flow approach using the following sources. If you use this software in your research, please cite Infinity Flow: High-throughput single-cell quantification of 100s of proteins using conventional flow cytometry and machine learning, Becht, Tolstrup, Dutertre, Ginhoux, Newell, Gottardo and Headley, 2020.

1. Our preprint
2. The peer-reviewed article - [pending]
3. An imaged digest of the paper

To learn how to apply the computational pipeline, check out the vignette: https://htmlpreview.github.io/?https://github.com/ebecht/infinityFlow/blob/master/doc/basic_usage.html

The package is currently pending publication on Bioconductor. In the meantime you can install it from github:

if(!require(devtools)){
	install.packages("devtools")
}
if(!require(infinityFlow)){
	library(devtools)
	install_github("ebecht/infinityFlow")
}