Incorporate knockTF as validation data
adamsardar opened this issue · comments
KnockTF catalogues 570 manually curated RNA-seq and microarray datasets associated with 308 TFs disrupted by different knockdown/knockout techniques and across multiple tissue/cell types. This is a fantastic validation set for the metaDEGth methodology (can we recover the TF given the regulon?).
We also need a source of regulons - use the ones in kockTF? Or perhaps use regulons from Dorothea?