ftd2xx is a simple python wrapper around the D2XX DLL from FTDI using ctypes. It is based on Pablo Bleyer Kocik's d2xx extension.
I am no longer developing this, but am accepting patches. I also don't have an FTDI setup to test this with. If you want to maintain the library, please let me know.
There is a more actively maintained library by Ben Bass called pylibftdi that you may be interested in.