ZaneMuir / CSHL-22-cross-orientation-interaction-V1

LNLN model modified from Barbera et al. 2022

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Modeling cross-orientation interactions in mouse V1

LNLN model modified from Barbera et al. 2022

People involved: Yizhan Miao

Short Abstract: In Barbera et al. 2022, model of V1 cell with only one subunit was used to simulate cross-orientation interactions in mouse. However, V1 neurons typically have an “on” and an “off” subunit. Here, I will build a new version of this model with "on" and "off" subunits and compare the magnitude and sensitivity of this interactions with those of the original model.

Milestones:

  1. replicate the model (LNLN model) from Barbera et al. 2022 in Python.
  2. modify the model with On and Off subunits and make comparisons
  3. time permitting, I will add "on-off" subunits to investigate if this type of relay cell would also contribute to the cross-orientation interactions in mouse.

PIs that are relevant: Lindsey Glickfeld

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LNLN model modified from Barbera et al. 2022


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