YakhiniGroup / SpectraPh

Extending partial haplotypes to full genome haplotypes using chromosome conformation capture data, Bioinformatics 2016

Home Page:http://bioinformatics.oxfordjournals.org/content/32/17/i559.short

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SpectraPh

Spectral Phasing Repository for "Extending partial haplotypes to full genome haplotypes using chromosome conformation capture data" paper published at ECCB2016 and Bioinformatics Vol32 Issue 17.

Code usage instructions:

Step 1. Compile and run SpectraPh.exe SAM2PSAM and follow instructions

Step 2. Run SpectraPh.exe PSAMBIN2CONTIGS and follow instructions

Step 3. Run Matlab ComputeCovariance.m

Step 4. Run Matlab ComputeEmbeddings.m

Step 5. Run Matlab ComputePhasing.m and see Results structure containing Phased HT-block ids per chromosome and their predicted haplotype id.

For additional help please be sure to read the github page, wiki and submit issues for any questions.

Animations are available at http://imgur.com/a/fwzBD

Relevant paper published at http://bioinformatics.oxfordjournals.org/content/32/17/i559.short

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Extending partial haplotypes to full genome haplotypes using chromosome conformation capture data, Bioinformatics 2016

http://bioinformatics.oxfordjournals.org/content/32/17/i559.short

License:Apache License 2.0


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