TheAthleticCoder / Ventral-Cochlear-Nucleus-Neurons

This repository aims to code out and replicate the results from the paper ' The Roles Potassium Currents Play in Regulating the Electrical Activity of Ventral Cochlear Nucleus Neurons.' Done as a part of the Monsoon'22 course 'Introduction to Neural Cognitive Modelling (INCM).'

The Roles Potassium Currents Play in Regulating the Electrical Activity of Ventral Cochlear Nucleus Neurons

Link for the research paper:

Rothman, Jason S, and Paul B Manis. “The roles potassium currents play in regulating the electrical activity of ventral cochlear nucleus neurons.” Journal of neurophysiology vol. 89,6 (2003): 3097-113. doi:10.1152/jn.00127.2002

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Objectives

We understand the existing work done in this field and come to the conclusion that The many discrepancies between the previous models and the new experimental data suggests that there is a need to examine the roles $K^+$ currents play in regulating the electrical activity of VCN neurons. More than anything in order to code it out, it became important to understand the VCN Somatic model, its biology and all the currents that describe it. After that, it became easy to code out the model and generate results.

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Libraries Used:

1. brian2
2. neurodynex

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File Structure

1. Ventral_Cochlear_Nucleus_Neurons.ipynb Code for the model specified in the paper as well as generated visual plots for the same.
2. presentation.pdf Slides used to present the work done in about 10 minutes.
3. report.pdf Report regarding the results generated and the work done in this project.

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