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Summer course content for Neuromatch Academy

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NeuroMatch Academy (NMA) syllabus

July 13-31, 2020

Objectives: Introduce traditional and emerging computational neuroscience tools, their complementarity, and what they can tell us about the brain. A main focus is on modeling choices, model creation, model evaluation and understanding how they relate to biological questions.

Tutorial microstructure: ~5min talk, ~15min hands-on (repeated)

Day structure: Opening keynote, 3h15min lecture/live Q&A/tutorial modules, 40min group discussion, 55min interpretation lecture (Outro) + live Q&As (what did we learn today, what does it mean, underlying philosophy). There will also be many networking activities (professional development sessions, yoga, social hangouts etc)! Details below.

Note for visitors from China: This repository contains many links to YouTube and Google Colab. We have a version of the repository with those same videos posted on bilibili, and the Google Colab links replaced with links to Aliyun. Please visit the China Accessible Neuromatch Course-Content

Prerequisites: See here

Course materials

Course outline


Week 1

Mon, July 13: Model Types

Description Introduce different example model types (Marr 1-3, what/how/why) and the kinds of questions they can answer. Realize how different models map onto different datasets.

Time (Hour) Lecture Details
-0:30-0:00* Intro / keynote & tutorial setup Model classifications
0:00-0:15 Pod Q&A Lecture discussion with pod TA
0:20-1:35 Tutorials + nano-lectures I "What"/"How" models
1:35-1:55 Discussion I Discussion with pod TA
1:55-2:55 Big break BREAK incl. 20min yoga session
2:55-4:10 Tutorials + nano-lectures II "Why" model & discussion
4:10-4:30 Discussion II Discussion with pod TA
4:35-5:05** Outro Recap session, The role of models in discovery
5:05-5:30 Q&A Q&A with lecturers/Mentors
5:30-6:30 Social hour Social hour

* the Intro / keynote will be watched asynchronously, which means that you can watch this lecture before the start of the day ** please watch the Outro on your own after having completed the tutorials and before the Q&A session


Tue, July 14: Modeling Practice

Description Introduction to the process of building models.

Time (Hour) Lecture Details
-0:30-0:00* Intro / keynote & tutorial setup How to approach modeling
0:00-0:15 Pod Q&A Lecture discussion with pod TA
0:20-1:35 Tutorials + nano-lectures I Framing the question
1:35-1:55 Discussion I Discussion with pod TA
1:55-2:55 Big break BREAK
2:55-4:10 Tutorials + nano-lectures II Model implementation and testing
4:10-4:30 Discussion II Discussion with pod TA
4:35-5:05** Outro Recap session, the modeling process
5:05-5:30 Q&A Q&A with lecturers/Mentors
5:30-6:30 Social hour Social hour

* the Intro / keynote will be watched asynchronously, which means that you can watch this lecture before the start of the day ** please watch the Outro on your own after having completed the tutorials and before the Q&A session


Wed, July 15: Model Fitting

Description Fit models to data, quantify uncertainty, compare models

Time (Hour) Lecture Details
-0:30-0:00* Intro / keynote & tutorial setup Why and how to fit models
0:00-0:15 Pod Q&A Lecture discussion with pod TA
0:20-1:35 Tutorials + nano-lectures I Fit a model 1 (linear regression), Get error bars
1:35-1:55 Discussion I Discussion with pod TA
1:55-2:55 Big break BREAK incl. 20min yoga session
2:55-4:10 Tutorials + nano-lectures II Compare models, cross-validation, hyperparameters, Fit a model 2 (nonlinear models)
4:10-4:30 Discussion II Discussion with pod TA
4:35-5:05** Outro Recap session, Critical evaluation of model fitting
5:05-5:30 Q&A Q&A with lecturers/Mentors
5:30-6:30 Social hour Social hour

* the Intro / keynote will be watched asynchronously, which means that you can watch this lecture before the start of the day ** please watch the Outro on your own after having completed the tutorials and before the Q&A session


Thu, July 16: Machine Learning: GLM

Description Introduction to machine learning. The commonly used approaches, how to avoid false positives, how to do it well

Time (Hour) Lecture Details
-0:30-0:00* Intro / keynote & tutorial setup We want to predict (scikit learn)
0:00-0:15 Pod Q&A Lecture discussion with pod TA
0:20-1:35 Tutorials + nano-lectures I Introduction to GLMs and predicting neural responses
1:35-1:55 Discussion I Discussion with pod TA
1:55-2:55 Big break BREAK incl. 20min yoga session
2:55-4:10 Tutorials + nano-lectures II Logistic regression, regularization, and decoding neural activity
4:10-4:30 Discussion II Discussion with pod TA
4:35-5:05** Outro Recap session, Promises and pitfalls of ML for Neuroscience
5:05-5:30 Q&A Q&A with lecturers/Mentors
5:30-6:30 Social hour Social hour

* the Intro / keynote will be watched asynchronously, which means that you can watch this lecture before the start of the day ** please watch the Outro on your own after having completed the tutorials and before the Q&A session


Fri, July 17: Dimensionality Reduction

Description Concept of dimensionality reduction, ways of doing it, what it means

Time (Hour) Lecture Details
-0:30-0:00* Intro / keynote & tutorial setup Manifolds to understand
0:00-0:15 Pod Q&A Lecture discussion with pod TA
0:20-1:35 Tutorials + nano-lectures I PCA 1 (orthonormal basis), PCA 2 (eigenvalues)
1:35-1:55 Discussion I Discussion with pod TA
1:55-2:55 Big break BREAK
2:55-4:10 Tutorials + nano-lectures II MNIST with PCA, MNIST with t-SNE
4:10-4:30 Discussion II Discussion with pod TA
4:35-5:05** Outro Recap session, The link between high-dimensional brain signals and low-dimensional behavior
5:05-5:30 Q&A Q&A with lecturers/Mentors
5:30-6:30 Social hour Social hour

* the Intro / keynote will be watched asynchronously, which means that you can watch this lecture before the start of the day ** please watch the Outro on your own after having completed the tutorials and before the Q&A session


Sat/Sun, July 18/19: Professional Development & Social

Description Professional development sessions and social activities will be offered on the weekend. More information, including exact times are available on the Neurostars Calendar



Week 2

Mon, July 20: Bayesian Statistics

Description Bayesian statistics, modeling of behavior, modeling of neural data, quantifying information

Time (Hour) Lecture Details
-0:30-0:00* Intro / keynote & tutorial setup Uncertainty
0:00-0:15 Pod Q&A Lecture discussion with pod TA
0:20-1:35 Tutorials + nano-lectures I Bayes rule: cue combination and marginalization
1:35-1:55 Discussion I Discussion with pod TA
1:55-2:55 Big break BREAK incl. 20min yoga session
2:55-4:10 Tutorials + nano-lectures II Bayesian Decision Theory & Causal inference
4:10-4:30 Discussion II Discussion with pod TA
4:35-5:05** Outro Recap session, Advanced Bayesian methods
5:05-5:30 Q&A Q&A with lecturers/Mentors
5:30-6:30 Social hour Social hour

* the Intro / keynote will be watched asynchronously, which means that you can watch this lecture before the start of the day ** please watch the Outro on your own after having completed the tutorials and before the Q&A session


Tue, July 21: Linear Systems

Description How to make estimates over time, how the brain does it

Time (Hour) Lecture Details
-0:30-0:00* Intro / keynote & tutorial setup World has time
0:00-0:15 Pod Q&A Lecture discussion with pod TA
0:20-1:35 Tutorials + nano-lectures I Linear systems theory I (ND deterministic) and Markov process
1:35-1:55 Discussion I Discussion with pod TA
1:55-2:55 Big break BREAK
2:55-4:10 Tutorials + nano-lectures II Linear systems theory II (1D stochastic = OU process; ND stocastic = AR(1)) and State space model
4:10-4:30 Discussion II Discussion with pod TA
4:35-5:05** Outro Recap session, Linear systems rule the world
5:05-5:30 Q&A Q&A with lecturers/Mentors
5:30-6:30 Social hour Social hour

* the Intro / keynote will be watched asynchronously, which means that you can watch this lecture before the start of the day ** please watch the Outro on your own after having completed the tutorials and before the Q&A session


Wed, July 22: Decision Making

Description How we can make decisions when information comes in over time

Time (Hour) Lecture Details
-0:30-0:00* Intro / keynote & tutorial setup We need to decide stuff
0:00-0:15 Pod Q&A Lecture discussion with pod TA
0:20-1:35 Tutorials + nano-lectures I Information theory, Sequential Probability Ratio Test (SPRT)
1:35-1:55 Discussion I Discussion with pod TA
1:55-2:55 Big break BREAK incl. 20min yoga session
2:55-4:10 Tutorials + nano-lectures II Hidden Markov Model inference (DDM), Kalman filter
4:10-4:30 Discussion II Discussion with pod TA
4:35-5:05** Outro Recap session, Decisions, decisions, decisions ...
5:05-5:30 Q&A Q&A with lecturers/Mentors
5:30-6:30 Social hour Social hour

* the Intro / keynote will be watched asynchronously, which means that you can watch this lecture before the start of the day ** please watch the Outro on your own after having completed the tutorials and before the Q&A session


Thu, July 23: Optimal Control

Description We need to move gain info and reach goals

Time (Hour) Lecture Details
-0:30-0:00* Intro / keynote & tutorial setup We want to control our actions...
0:00-0:15 Pod Q&A Lecture discussion with pod TA
0:20-1:35 Tutorials + nano-lectures I Expected utility / Cost, Markov decision process (MDP)
1:35-1:55 Discussion I Discussion with pod TA
1:55-2:55 Big break BREAK incl. 20min yoga session
2:55-4:10 Tutorials + nano-lectures II LQG control (MDP for linear systems), Motor control (signal-dependent noise, time cost, ...)
4:10-4:30 Discussion II Discussion with pod TA
4:35-5:05** Outro Recap session, Advanced motor control
5:05-5:30 Q&A Q&A with lecturers/Mentors
5:30-6:30 Social hour Social hour

* the Intro / keynote will be watched asynchronously, which means that you can watch this lecture before the start of the day ** please watch the Outro on your own after having completed the tutorials and before the Q&A session


Fri, July 24: Reinforcement Learning

Description The setting of reinforcement learning and how it approximates the real world, behavior, and potential brain implementations

Time (Hour) Lecture Details
-0:30-0:00* Intro / keynote & tutorial setup Problem formulations: actor-critic
0:00-0:15 Pod Q&A Lecture discussion with pod TA
0:20-1:35 Tutorials + nano-lectures I Critic: reward prediction error, Exploration (POMDP) vs exploitation
1:35-1:55 Discussion I Discussion with pod TA
1:55-2:55 Big break BREAK
2:55-4:10 Tutorials + nano-lectures II Model-based vs model-free RL, Multi-arm bandits: foraging
4:10-4:30 Discussion II Discussion with pod TA
4:35-5:05** Outro Recap session, RL and the brain
5:05-5:30 Q&A Q&A with lecturers/Mentors
5:30-6:30 Social hour Social hour

* the Intro / keynote will be watched asynchronously, which means that you can watch this lecture before the start of the day ** please watch the Outro on your own after having completed the tutorials and before the Q&A session


Sat/Sun, July 24/25: Professional development & Social

Description Professional development sessions and social activities will be offered on the weekend. More information, including exact times are available on the Neurostars Calendar



Week 3

Mon, July 27: Real Neurons

Description The things neurons are made of, channels, morphologies, neuromodulators, and plasticity

Time (Hour) Lecture Details
-0:30-0:00* Intro / keynote & tutorial setup Real neurons ftw
0:00-0:15 Pod Q&A Lecture discussion with pod TA
0:20-1:35 Tutorials + nano-lectures I Reduced neuron models and transfer of synchrony
1:35-1:55 Discussion I Discussion with pod TA
1:55-2:55 Big break BREAK incl. 20min yoga session
2:55-4:10 Tutorials + nano-lectures II Short-term plasticity of synapses and Hebbian plasticity & STDP
4:10-4:30 Discussion II Discussion with pod TA
4:35-5:05** Outro Recap session, A variety of neuron models
5:05-5:30 Q&A Q&A with lecturers/Mentors
5:30-6:30 Social hour Social hour

* the Intro / keynote will be watched asynchronously, which means that you can watch this lecture before the start of the day ** please watch the Outro on your own after having completed the tutorials and before the Q&A session


Tue, July 28: Dynamic Networks

Description How single neurons create population dynamics

Time (Hour) Lecture Details
-0:30-0:00* Intro / keynote & tutorial setup Mechanistic models of different types of brain actvivity
0:00-0:15 Pod Q&A Lecture discussion with pod TA
0:20-1:35 Tutorials + nano-lectures I 2D dynamical systems, Wilson-Cowen model (coarse-grained), oscillations & synchrony
1:35-1:55 Discussion I Discussion with pod TA
1:55-2:55 Big break BREAK
2:55-4:10 Tutorials + nano-lectures II Attractors & local linearization around fixed points, Balanced Amplification & Inhibition-stabilized network
4:10-4:30 Discussion II Discussion with pod TA
4:35-5:05** Outro Recap session, A theory of the whole brain
5:05-5:30 Q&A Q&A with lecturers/Mentors
5:30-6:30 Social hour Social hour

* the Intro / keynote will be watched asynchronously, which means that you can watch this lecture before the start of the day ** please watch the Outro on your own after having completed the tutorials and before the Q&A session


Wed, July 29: Network Causality

Description Ways of discovering causal relations, ways of estimating networks, what we can do with networks

Time (Hour) Lecture Details
-0:30-0:00* Intro / keynote & tutorial setup Causality - different views
0:00-0:15 Pod Q&A Lecture discussion with pod TA
0:20-1:35 Tutorials + nano-lectures I Pittfalls of Granger and Centrality
1:35-1:55 Discussion I Discussion with pod TA
1:55-2:55 Big break BREAK incl. 20min yoga session
2:55-4:10 Tutorials + nano-lectures II Instrumental Variables and interventions
4:10-4:30 Discussion II Discussion with pod TA
4:35-5:05** Outro Recap session, Ladders of causality
5:05-5:30 Q&A Q&A with lecturers/Mentors
5:30-6:30 Social hour Social hour

* the Intro / keynote will be watched asynchronously, which means that you can watch this lecture before the start of the day ** please watch the Outro on your own after having completed the tutorials and before the Q&A session


Thu, July 30: Deep Learning 1

Description The concept of ANNs, how to train them,what they are made out of, convnets, and how to fit them to brains

Time (Hour) Lecture Details
-0:30-0:00* Intro / keynote & tutorial setup DL = crucial tool
0:00-0:15 Pod Q&A Lecture discussion with pod TA
0:20-1:35 Tutorials + nano-lectures I Pytorch intro & model components, Training it & inductive bias
1:35-1:55 Discussion I Discussion with pod TA
1:55-2:55 Big break BREAK incl. 20min yoga session
2:55-4:10 Tutorials + nano-lectures II Convolutional Neural Network, Fit to brain (RSA - represenatational similarity analysis)
4:10-4:30 Discussion II Discussion with pod TA
4:35-5:05** Outro Recap session, Digging deep
5:05-5:30 Q&A Q&A with lecturers/Mentors
5:30-6:30 Social hour Social hour

* the Intro / keynote will be watched asynchronously, which means that you can watch this lecture before the start of the day ** please watch the Outro on your own after having completed the tutorials and before the Q&A session


Fri, July 31: Deep Learning 2

Description Deep learning in more advanced settings. Autoencoders for structure discovery, RNNs, and fitting them to brains

Time (Hour) Lecture Details
-0:30-0:00* Intro / keynote & tutorial setup DL for structure
0:00-0:15 Pod Q&A Lecture discussion with pod TA
0:20-1:35 Tutorials + nano-lectures I Variational autoencorders and uses in Neuroscience
1:35-1:55 Discussion I Discussion with pod TA
1:55-2:55 Big break BREAK
2:55-4:10 Tutorials + nano-lectures II NMA wrap-up
4:10-4:30 Discussion II Discussion with pod TA
4:35-5:05** Outro Recap session, Digging deeper
5:05-5:30 Q&A Q&A with lecturers/Mentors
5:30-6:30 Social hour Social hour

* the Intro / keynote will be watched asynchronously, which means that you can watch this lecture before the start of the day ** please watch the Outro on your own after having completed the tutorials and before the Q&A session


Networking (throughout) - interactive track only

  • Meet a prof about your group's project
  • Meet a prof about your career
  • Meet a prof about your own project
  • Meet other participants interested in similar topics
  • Meet a group of likeminded people
  • Meet people that are local to you (same city, country)

Group projects (throughout) - interactive track only

TBA


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Summer course content for Neuromatch Academy

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