MRCBSU / PC-GMM

R code for an application of cis-multivariable Mendelian randomization to GLP1R gene region

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Cis-multivariable Mendelian randomization using robust PCA-GMM

R code to apply the methods discussed in "Robust use of phenotypic heterogeneity at drug target genes for mechanistic insights: application of cis-multivariable Mendelian randomization to GLP1R gene region"

  • R code to run the method: PCA-GMM.R
  • R code walkthrough to reproduce empirical findings: GLP1R-analysis.pdf

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R code for an application of cis-multivariable Mendelian randomization to GLP1R gene region


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