GeneticResources / polygenic-risk-scores

Script to calculate polygenic risk scores in a genotyped sample using GWAS summary statistics from a disease/trait.

polygenic-risk-scores

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Author

Padhraig Gormley

Massachusetts General Hospital | Broad Institute of MIT and Harvard.

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Synopsis

Script for calculating polygenic risk scores in a genotyped sample using GWAS summary statistics from a disease/trait.

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Dependencies

PLINK (https://www.cog-genomics.org/plink2)

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Usage

Open your bash or other shell. Then to run the script with the supplied toy data type:

sh ./calc-PRS-scores.sh myStudyName imputedSampleRootName GWASresultsFile