All .r program files is describe about APCES and other algorithm and Classification_Main(xxxx).R is the main program of each algorithm. If you want to use this program, please follow this steps: 1: First of all you should do some preparatory work, before the program can be executed you may need to download some r language packages, you can use the install.packages() command or to search on Bioconductor website. 2: Use Dataset_Init.R program to preprocess data in Datasets . 3:Use Classification_Main (xxxx) .R to computing classification result of preprocessed data.