This project is part of the RNA Systems Biology Lab at BioISI - BioSystems and Integrative Sciences Institute. For other group projects, please visit our GitHub page.
- Alexandre Coelho (afdcoelho@fc.ul.pt)
- Gonçalo Nogueira (grnogueira@fc.ul.pt)
- João Miranda (jamiranda@fc.ul.pt)
- Francisco Pinto (frpinto@fc.ul.pt)
For additional information, please contact Francisco Pinto [frpinto@fc.ul.pt].
GAP-MINE is an algorithm for the prediction of gene associations with diseases and cell processes. This algorithm is composed of the following steps:
- Graph Construction (Biological Network);
- Proximity Metric Computation;
- Additional Module Selection (Embedding Construction);
- New Association Prediction.
Additionally, this repository also contains several notebooks for the visualization of the obtained results and the validation of the new predictions.
- Python
- R
- jupyter
- Pandas
- NumPy
- SciPy
- scikit-learn
- OPLS-DA
- goatools
- Paper Figures
- Embedding Explainability
- GO and HPO Enrichment Analysis