Christini Lab at Weill Cornell Medical College's repositories
automated-ipsc-cardiotoxicity
Study of drug cardiotoxicity using iPSC-derived cardiomyocytes with the Nanion Patchliner
ap-heterogeneity-review
Repository to plot Figure 1 from Symposium Review
nav_artifact
A repository for NaV artifact project simulation and figures
artifact_project
Contains all simulation and analysis related to my (Alex) artifact project
iPSC-leak-artifact
Simulations and figures for manuscript showing descriptive ability of iPSC-CM+artifact models
iPSC-genetic-algorithm
An optimized voltage protocol for isolating individual currents
vc-optimization-cardiotoxicity
Includes all the modeling, genetic algorithm simulations, and data analysis for the Christini Lab paper on drug cardiotoxicity screening with an optimized VC protocol
cell-models
A flexible Python package for installing various cell models, including: Kernik, Paci 2018, and O'Hara Rudy
RTXI-data-analysis-toolkit
A collection of tools for processing RTXI output data
DynClamp_IScale_GA_Fitting
Experimental measurements from guinea pig ventricular myocytes of dynamic clamp perturbations are used to fit the behavior of the Livshitz Rudy 2009 ventricular model.
Ortega_LivshitzRudy2009
Modified version of the Livshitz Rudy 2009 guinea pig ventricular cardiomyocyte model.
Genetic_Algorithm
Christini lab version of a genetic algorithm, based on the Kurama Sastry GA from the Illinois Genetic Algorithms Laboratory.
RTXI_Membrane_Test
Membrane test electrophysiology module to calculate resistance and membrane properties during patch clamp experiments.
RTXI_Repolarization_Reserve_Current
RTXI module to estimate and inject the minimum bias current required to reverse repolarization.
RTXI_AP_Clamp
RTXI 2.0 module for action potential clamp.