AlexdeMendoza / BrainZoo

Scripts used in brain mCH manuscript

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BrainZoo

Files and code used for de Mendoza, A., Poppe, D., Buckberry, S. et al. "The emergence of the brain non-CpG methylation system in vertebrates". Nat Ecol Evol (2021). https://doi.org/10.1038/s41559-020-01371-2

Code

  • MasterScript_BrainZoo.R
  • ATCGmap_GenotypeCorrector.sh

Files

  • DNMT3.phylogeny: Amino acid sequence alignments and phylogeny of DNMT3 orthologues.
  • MECP2_MBD4.phylogeny: Amino acid sequence alignments and phylogeny of MECP2/MBD4/MBD1-2-3 orthologues.
  • Kallisto_brain_samples.tar.gz: Kallisto output files for brain RNA-seq samples for every species.
  • mCH_stats.tsv: Global mCH levels for each brain WGBS sample.
  • all_GOs_simplified.csv.gz: gProfiler Gene Ontology lists for each species divided by top mCA, bottom mCA, top mCG, bottom mCG.

About

Scripts used in brain mCH manuscript

License:MIT License


Languages

Language:R 87.1%Language:Shell 12.9%