AlexandrovLab / SigProfilerSingleSample

SigProfilerSingleSample allows attributing a known set of mutational signatures to an individual sample. The tool identifies the activity of each signature in the sample and assigns the probability for each signature to cause a specific mutation type in the sample. The tool makes use of SigProfilerMatrixGenerator and SigProfilerPlotting.

AlexandrovLab/SigProfilerSingleSample Issues

copy number signature
Closed 7 months ago1
index out of range
Closed a year ago3
KeyError: '7_pvalue'
Closed a year ago1
Can ID signatures be run on vcfs from build 38?
Closed a year ago1
Sigprofiler single sample decomposition profile doesn't match match COSMIC signature database?
Closed 2 years ago1
IndexError when run with GRCh38
Closed 2 years ago2
SigProfilerSingleSample not used by CNV signature
Closed 2 years ago1
Error when running SigProfilerSingleSample.
Closed 2 years ago4
Vcf input doesn't work with other signatures than default ones
Closed 3 years ago10
New signatures on COSMIC website
Closed 3 years ago7
implementation for mutational catalogue as input
Closed 3 years ago4
gzip VCF files
Closed 3 years ago1
Can this tool be used with a different genome?
Closed 3 years ago1
Assignment of mutational signatures with SigProfilerSingleSample
Closed 3 years ago
S should be uppercase for filename "signatures.txt" in spss.py script
Closed 3 years ago8
DBS and Indels signature missing
Closed 3 years ago
ID decomposition support?
Closed 4 years ago2
minimum threshold for reported signatures?
Closed 4 years ago1
Missing Subfolders
Closed 4 years ago1
DBS and ID mutational signatures?
Closed 4 years ago1
Input differs than output of SigProfilerExtractor
Closed 4 years ago10
Test tool compatibility on Windows and Linux
Closed 5 years ago1