zhangzlab / covid_balf

R script for the covid balf data analysis

Geek Repo:Geek Repo

Github PK Tool:Github PK Tool

Control Sex effects during scaling and DEG analysis

opened this issue · comments

Hi,

Thank you for sharing all the resources and codes.
Have you noticed or tried to regress out gender effects during scaling or DEG analysis?

No, we didn't control sex effects in the analysis. You can try whether gender effect has much influence on the final results.

Cool. Thank you!
I had a problem where Xist and other sex-related genes alwalys came up when I did DEGs analysis. I'm trying to figure out what is the best way to regress out sex effects in Seurat package.