Ability to add flat files for options and skip complex regions.
srynobio opened this issue · comments
Shawn Rynearson commented
Considering a few WHAM-GRAPHING options:
Required:
-f - <STRING> - A sorted and indexed bam file or a list
of bams: a.bam,b.bam,...
Optional:
-e - <STRING> - Comma sep. list of seqids to skip [false].
-r - <STRING> - Region in format: seqid:start-end [whole genome]
- It would be helpful if you could supply flat files for all three of these options. As opposed to supplying long lists of comma separated files.
./WHAM-GRAPHING -f reference.fasta -f bam_files.txt -r regions.bed
.
This would improve not only ease of use, but allow better cohort and targeted gene analysis.
- It would be nice to have the ability to tell WHAM regions to downsample or skip altogether.
./WHAM-GRAPHING -f reference.fasta -f bam_files.txt --skip complexity_regions.bed
. - Also a bit more clarity on how the -r option works in regards to calling SV and genotyping.