ERVcaller is a tool designed to accurately detect and genotype non-reference unfixed endogenous retroviruses (ERVs) and other transposable elements (TEs) in the human genome using next-generation sequencing (NGS) data. We evaluated the tools using both simulated and real benchmark whole-genome sequencing (WGS) datasets. ERVcaller is capable to accurately detect various TE insertions of any lengths, particularly ERVs. It allows for the use of a TE reference library regardless of sequence complexity, such as the entire RepBase database. It is easy to install and use with command lines.
ChristopherLeeZG opened this issue · comments
你好，陈博，readme里面写到本软件会包含SE_MEI的脚本，但是我并没有看到。
于是我到SE_MEI原作者的GitHub里面下载安装了SE_MEI（改了htslib的版本为1.1），可以跑通ERVcaller，请问这也可以吗。
谢谢大神！
您好，你可以在ERVcaller软件的Scripts/ 文件夹下面找到对应的压缩文件。原始版本的SE_MEI script并不能产生所需要的信息，因此尽管可以跑通ERVcaller，也无法有效使用split reads
chen
好的，谢谢陈博！