======================================= Top-DBS 1.0 Prediction of beta-strand pairs, beta-strand pairing direction, and beta-sheet topology Knowledge Engineering Research Group (KERG), Department of Computer Engineering, Faculty of Engineering, Ferdowsi University of Mashhad, Iran. Home page: https://kerg.um.ac.ir/ ; Email: kerg@um.ac.ir Contact: Toktam Dehghani Ph.D. Candidate and Researcher, Department of Computer Science and Software Engineering, Faculty of Engineering, Ferdowsi University of Mashhad, Iran. Dehgani.toktam@mail.um.ac.ir Copyright (C) 2018 Toktam Dehghani The program is free for scientific/academic use. The software must not be further distributed without prior permission of the author. ======================================= Top-DBS can be downloaded from "http://kerg.um.ac.ir/" In order to run Top-DBS the following information must be provided: 1. Secondary structure information (beta-strands and beta-residue) 2. A beta-residue contact score matrix 3. A beta-strand pairwise alignment matrix The program will provide in output the following information: 1. Beta-strand pairs 2. Beta-strand pairing direction 3. Beta-sheet topology ***Examples files contained in the example folder. ======================================= Installation (Windows Version): 1. Unzip Top-DBS.rar 2. Input file: a Beta-strand pairwise alignment matrix [example\1nega\1nega.txt] 3. Build and Run Top-DBS.exe 4. Output file: Beta-sheet topology [example\1nega\1nega.out] ***Correct answer is provided in following address: [example\1nega\1nega.str] Enjoy it! ======================================= For more information about file formats, please refer to README.txt Contact: Dehgani.toktam@mail.um.ac.ir