satijalab / seurat

R toolkit for single cell genomics

Home Page:http://www.satijalab.org/seurat

Repository from Github https://github.comsatijalab/seuratRepository from Github https://github.comsatijalab/seurat

BUG: FindVariableFeatures didnt work on my PCs

OrcowrkerFUSCC opened this issue · comments

Issue Description

Hi,i had some trouble with analysis of some data with seurat v4 and v5.0.3
I found that seurat v5.1.0 and didnt work with seurat v5.0.3 and all seurat v4
I install seurat through conda and this is the session information

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When I run findvaribalefeatures the second step seems to use nearly all my cores and stuck there

Image

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The most weird thing is I do the same job in my laptop with the exact same version of ubuntu and R and so on ,and that works well, but my laptop is inferior to my PCs, so I'm willing to figure out the reason.
Another information is When I spilit object, it can still works.
This is my data

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Reproducing Code Example

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Error Message

Additional Comments

No response

Session Info

see above figure

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and this is how v5.1.0 works

If the issue is affecting multiple versions of Seurat and is isolated to a single machine, then the problem is probably not with Seurat.