Question: IMC and single cell resolution ST data

[Sara Patti]

Hi!

Really interested in trying to use MISTy for some IMC and single cell resolution spatial transcriptomics data. I saw in the paper that you analyzed very similar data types and you have those workflows in R. However, I am hoping to do this in python rather than R.

I looked at the tutorial (https://liana-py.readthedocs.io/en/latest/notebooks/misty.html#Extract-Cell-type-Composition) and it used Visium data, so I wanted to see if there were any tutorials in python on the workflow/pipeline to analyze single cell resolution data?
If not, would you be able to share with me how I can use MISTy to analyze IMC or Xenium ST data in Python?

Thanks!