Giters

quadbio / Pando

Multiome GRN inference.

Home Page:https://quadbio.github.io/Pando/

Geek Repo:Geek Repo

Github PK Tool:Github PK Tool

model overfitting

tkisss opened this issue · comments

commented

Hi,

I noticed that Pando utilizes regression models like GLM to fit gene expression based on TF expression and chromatin accessibilities without dividing the data into training and test sets. Can I infer that in this scenario, the model is prone to overfitting? Does this strategy provide any benefits for gene expression regulation?