Question: Can Pando be used on an unpaired multiomic dataset?

[mitchTwoTimes]

Is it possible to make a GRN using Pando on an integrated object like the one described here?

Thank you

[jonas]

Pando can be used on any object that has both RNA and ATAC modalities for each sample/cell. If one integrates two datasets and summarizes them into metacells or high-resolution clusters, this should work. We have done something similar here: https://www.nature.com/articles/s41586-022-05279-8