nextstrain / nextclade

Viral genome alignment, mutation calling, clade assignment, quality checks and phylogenetic placement

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Is there any example for handling HIV data?

liamxg opened this issue · comments

commented

Dear @ivan-aksamentov,

Could I know if there is any example for handling HIV data to run alignment, mutation calling, clade assignment, quality checks and phylogenetic placement?

@liamxg There isn't at this time, but we experimented internally a little with it. There is a few problems to solve with regards to HIV, because it's a very diverse virus.

In Nextclade v3 it will be easier to create datasets, so you could create your own (or multiple of them). Here is a preview of how it might look like in Nextclade v3: https://github.com/nextstrain/nextclade_data/blob/master/docs/dataset-curation-guide.md

commented

Dear @ivan-aksamentov,

Thanks. Agree with you that HIV is a very diverse virus. I will look for Nextclade v3 first.