Merck Sharp & Dohme Corp. a subsidiary of Merck & Co., Inc. (Merck)

Merck Sharp & Dohme Corp. a subsidiary of Merck & Co., Inc.

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Merck Sharp & Dohme Corp. a subsidiary of Merck & Co., Inc.'s repositories

BioPhi

BioPhi is an open-source antibody design platform. It features methods for automated antibody humanization (Sapiens), humanness evaluation (OASis) and an interface for computer-assisted antibody sequence design.

Language:PythonLicense:MITStargazers:130Issues:10Issues:53

r2rtf

Easily Create Production-Ready Rich Text Format (RTF) Table and Figure

Language:RLicense:GPL-3.0Stargazers:76Issues:13Issues:113

matcher

Matcher is a tool for understanding how chemical structure optimization problems have been solved. Matcher enables deep control over searching structure/activity relationships (SAR) derived from large datasets, and takes the form of an accessible web application with simple deployment. Matcher is built around the mmpdb platform.

Language:PythonLicense:MITStargazers:51Issues:12Issues:11

rdf2x

RDF2X converts big RDF datasets to the relational database model, CSV, JSON and ElasticSearch.

Language:JavaLicense:Apache-2.0Stargazers:46Issues:7Issues:4

pkglite

Compact Package Representations

Language:RLicense:GPL-3.0Stargazers:29Issues:9Issues:36

Line-of-Therapy-Algorithm

This is the Line of Therapy Algorithm, as described in the paper "Temporal phenotyping by mining healthcare data to derive lines of therapy for cancer" pending submission in the Journal of Biomedical Informatics.

Language:PythonLicense:GPL-3.0Stargazers:26Issues:8Issues:0

sonar-r-plugin

Adds support for R language into SonarQube. It uses output from lintr tool which is processed by the plugin and uploaded into SonarQube server.

Language:JavaLicense:Apache-2.0Stargazers:24Issues:8Issues:17

AlgebraicAgents.jl

A lightweight framework to enable hierarchical, heterogeneous dynamical systems co-integration. Batteries included!

Language:JuliaLicense:NOASSERTIONStargazers:20Issues:5Issues:15

ReactiveDynamics.jl

A Julia package that implements a category of reaction (transportation) network-type dynamical systems.

Language:JuliaLicense:NOASSERTIONStargazers:17Issues:5Issues:8

gsDesign2

Group Sequential Design Under Non-Proportional Hazards

Language:RLicense:GPL-3.0Stargazers:15Issues:11Issues:189

metalite.ae

An R package for standard adverse events analysis

Language:RLicense:GPL-3.0Stargazers:15Issues:7Issues:73

simtrial

Clinical trial simulation for time-to-event endpoints

Language:RLicense:GPL-3.0Stargazers:15Issues:10Issues:78

metalite

An R package to create metadata structure for ADaM data analysis and reporting

Language:RLicense:GPL-3.0Stargazers:14Issues:9Issues:65

boxly

Interactive box plot for clinical trial analysis

Language:RLicense:GPL-3.0Stargazers:13Issues:6Issues:22

forestly

Interactive forest plot for adverse events analysis

Language:RLicense:GPL-3.0Stargazers:11Issues:7Issues:18
Language:Jupyter NotebookLicense:NOASSERTIONStargazers:11Issues:8Issues:8

GeneratedExpressions.jl

A Julia package that implements a metalanguage to support expression comprehensions.

Language:JuliaLicense:NOASSERTIONStargazers:9Issues:7Issues:1

gMCPLite

Lightweight graph-based multiple comparison procedures

Language:RLicense:GPL-3.0Stargazers:8Issues:7Issues:14

psm3mkv

psm3mkv: A package to evaluate the fit and efficiency of three state oncology cost-effectiveness model structures

Language:RLicense:GPL-3.0Stargazers:8Issues:7Issues:1

AbLEF

Antibody Langauge Ensemble Fusion - fuses antibody structural ensemble and language representation for property prediction

Language:PythonStargazers:7Issues:8Issues:0

CEEDesigns.jl

A decision-making framework for the cost-efficient design of experiments, balancing the value of acquired experimental evidence and incurred costs.

Language:JuliaLicense:NOASSERTIONStargazers:7Issues:8Issues:6

gMCPShiny

A Shiny app for graphical multiplicity control

Language:RLicense:GPL-3.0Stargazers:7Issues:7Issues:2

MolPROP

fuses molecular language and graph representation for property prediction

Language:PythonStargazers:4Issues:0Issues:0
Language:PythonLicense:Apache-2.0Stargazers:3Issues:5Issues:0

simvaxpmx

Elucidating vaccine efficacy using a correlate of protection, demographics, and logistic regression

Language:RLicense:NOASSERTIONStargazers:3Issues:0Issues:0
Language:HTMLStargazers:1Issues:5Issues:0

wpgsd

Weighted parametric group sequential design

Language:RLicense:GPL-3.0Stargazers:1Issues:6Issues:13
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Language:RLicense:GPL-3.0Stargazers:0Issues:5Issues:0

metalite.sl

An R package designed for the analysis & reporting of subject baseline characteristics in clinical trials.

Language:RLicense:GPL-3.0Stargazers:0Issues:5Issues:6