marislab / pptx-pdx-fusion-analysis

Fusion pipeline and figures

PPTC PDX Fusion Pipeline

Authors:	Komal S. Rathi
Contact:	Komal S. Rathi ([e-mail])
Organization:	CHOP
Status:	Completed
Date:	2024-08-16

Introduction

This repo contains code for:

1. Fusion detection and filtering
2. Create publication quality figures.

Details

• get_data.R: Pull raw input data from figshare
• update_fusion_output.R: Updates obsolete Hugo gene symbols in raw input data
• driver_fusions.R: Driver fusion results from cytogenetics/literature search
• venn_diagram.R: Creates venn diagram of driver fusions
• summary: Creates combined excel sheet with Fusion detection/filtering pipeline + driver fusions