Can latest `derfinder` reproduce original (2013) analysis?
brianhigh opened this issue · comments
Can the analysis in the paper Differential expression analysis of RNA-seq data at single-base resolution be reproduced using the latest version of derfinder? I ask because I am having a difficult time doing so using the "beta" version of the code and analysis_code.R. Thanks for any help you can provide.
The software from the 2013 paper is different from this one as they use different statistical models. If you want to reproduce those results use https://github.com/alyssafrazee/derfinder
You can alternatively use this derfinder implementation to compare the results. Aka, replicate but not reproduce.