icbi-lab / nf-deseq2

A RNA-seq differential expression analysis pipeline downstream of nf-core/rnaseq.

Geek Repo:Geek Repo

Github PK Tool:Github PK Tool

Add module for variancePartition

vjmarteau opened this issue · comments

How does that relate to RUVSeq/SVA (#18)?

If you add "batch" as factor you can nicely see how much variance is accounted for by batch effects. So far I have not only used the variancePartition package to check if batch effects have been removed after normalization (as suggested in #18), but also looked at the amount of variation that is explained by biological factors.