icbi-lab / infercnvpy

Infer copy number variation (CNV) from scRNA-seq data. Plays nicely with Scanpy.

Home Page:https://infercnvpy.readthedocs.io/en/latest/

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Add wrapper for copyKAT

grst opened this issue · comments

copyKAT has recently been released and appears to be superior over the infercnv method. While it might not be worth the effort reimplementing their algorithm in python, it would be nice to
have a wrapper function around their R code from the infercnvpy interface.

This would also enable downstream analysis using the infercnvpy visualization tools and creating the CNV-based umap based on copyKAT.

It would probably go into a separate tool: cnv.tl.copykat.

@chris-rands, @JBreunig, @rgranit, a copyKAT wrapper is now available as infercnvpy.tl.copykat and released in v0.2.0.

A working R installation with the copykat package installed is required for it to work.

Let me know if you have any feedback!

Thanks @grst I'll check it out (literally)