Large TDs spanning the window size lose supporting reads
RobinVanSchendel opened this issue · comments
When I run Pindel on a windowsize of 1 -w 1 and I have TDs in my background, TDs that overlap a window get very little supporting reads. For example:
TD 613012 NT 0 "" ChrID 2 BP 17952802 18565815
run on window size 5:
genotypeX 29 19 8 8 16 13
but on window size 1:
genotypeX -1 18 8 8 6
is this expected behaviour and should I not use a smaller window size?