definition of some parameters when simulate SV

[charliechen912ilovbash]

Hi,

I have few questions about simulating SV that I couldn't find any answers in the tutorial:

1. what does homozygous_ratio means in parameter_file for simSV
2. what does SNP mutations frequency means in simSV
3. what does scanreads do and what is the meaning of error profile file in simreads
   For example, does any nanopore reads from normal human is appropriate as the input of scanreads?

Thank you very much

[Fritz Sedlazeck]

1. Rate of het vs hom Snv
2. Frequency of random Snv mutations
3. Scan reads can measure error and size distribution that then can be used for simulating long reads
   Hope that helps
   Fritz

[charliechen912ilovbash]

Thanks for the quick reply!