Support for structural rearrangements
jmur14 opened this issue · comments
Could ideogram support circular diagrams to depict ring chromosomes?
This is intriguing. Could you briefly explain how this would be useful to support in Ideogram?
Cytogeneticists have to rely on something like cydas.org to draw the chromosomal abnormality like a ring and the terminal deletions on both ends of the chromosome. However, there is no easy way to depict in picture form what the resultant abnormal ring would look like. There are no tools to create the ring from the abnormal ideogram.
Thanks, the explanation and image are helpful. I see the image shows a linear chromosome, yet you'd like a circular ring, thus your feature request here. I sympathize with a desire for cytogenetic convention and more biological realism, even though the linear form might abstractly convey key information.
For convenient reference, here's a ring chromosome image I found from Garsed DW, Holloway AJ, Thomas DM. Cancer-associated neochromosomes: a novel mechanism of oncogenesis. Bioessays. 2009 Nov;31(11):1191-200. doi: 10.1002/bies.200800208. PMID: 19795405.
Is the ring chromosome in B above basically what you're looking for? If not, can you attach some reference image(s) here, for how you'd ideally like these ring chromosomes to look?