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editasmedicine / calitas

This repository is home to CALITAS, a CRISPR-Cas-aware ALigner for In silico off-TArget Search. CALITAS implements a customized gapped alignment of guide sequences to genomes and other reference sequences, returning consistent and non-redundant alignments.

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SearchReference with -v vcf file takes forever

YichaoOU opened this issue · comments

commented

Hello,

All work great with calitas SearchReference.

But once I included a vcf file -v vcf -c chrY, even for chrY, it has been24 hours and still not finished. Is it normal?

Thanks,
Yichao