dosorio / Peptides

An R package to calculate indices and theoretical physicochemical properties of peptides and protein sequences.

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Assigning peptide N- or C-termini labels when calculating mw/mz

tobimaile opened this issue · comments

Hey there!

Awesome package, thank you!

I was wondering if aaShift within mz/mw could be extended for a function to label peptide-termini besides specific aminoacids?

This would be very useful for example when adding labels to the termini of peptides.

In the case of TMT-tags, they would be even cumulative with N-terminus and specific aminoacids such as K (a N-terminal K would carry two TMT-labels, one on the amino group of the free peptide terminus and one on free amino group in the sidechain).

Cheers,
Tobias

Hey there!

Sorry for not seeing this before ... but as an alternative you could make a helper function that combines aaComp with your tag of interest.

LMK if that would help
best,
Sebastian