chrchang / plink-ng

A comprehensive update to the PLINK association analysis toolset. Beta testing of the first new version (1.90), focused on speed and memory efficiency improvements, is finishing up. Development is now focused on building out support for multiallelic, phased, and dosage data in PLINK 2.0.

Home Page:https://www.cog-genomics.org/plink/2.0/

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Wrong ordering in physical positions

zillurbmb51 opened this issue · comments

Hi,
I was trying to phase my genotype data using shapeit2 after qc with plink. Shapeit2 is giving me error:
Wrong ordering in physical positions curr_pos=#### prev_pos=####
Is there any way to fix this issue?
I have tried to use --update-chr and --update-map with HRC reference panel but the error exist.
Any help?
Uploading wrong-ordering-in-physical-positions.png…

It sounds like you need to use --sort-vars on your dataset.

Thanks a lot. I was trying to use as : plink2 --bfile my_plink --sort-vars --make-bed --out my_plink_sorted
It produces bim and fam file but not bed. The message is: Error: Fixed-width .bed/.pgen output doesn't support sorting yet. Generate a regular sorted .pgen first, and then reformat it.

Any help? How could I create a regular sorted bed file?
chr1.step12.log

Then I tried to make pgen first and then bed but failed. If I use plink2 --bfile chr4.step11 --sort-vars n --make-pgen --out chr4.step12
and then plink2 --pfile chr4.step12 --make-bed --out chr4.step13

and try phasing chr4.step13 but it gives me previous error: Wrong ordering in physical positions curr_pos=77809318 prev_pos=190915650

Please post usage questions like this in the plink2-users Google group, not here; and make sure to include full .log files.