Diabetic Retinopathy Detection by Retinal segmentation with Region merging using CNN
Diabetic retinopathy is a state of eye infirmity in which damage arises due to diabetes mellitus. It is one of the prominent reasons behind blindness. Most of new cases of diabetic retinopathy can get reduced with proper treatment of eyes
Stages Of Diabetic Retinopathya
Mild nonproliferative retinopathy
During the early stage of the disease microaneurysms occures. microaneurysms are small areas where balloon-like swelling occurs in the blood vessels of the retina. It causes the fluid to leak into the retina.
Moderate
nonproliferative retinopathy.While the disease advances, the blood vessels begin to swell and distort. This completely affects their ability to transport blood. These conditions incite change in the appearance of the retina.
Severe
nonproliferative retinopathy.During this state blood vessels gets completely blocked. This seizes blood supply to areas of the retina. These areas disguise growth factors and gives signal the retina to grow new blood vessels.
Proliferative diabetic retinopathy (PDR)
This is the highest stage of severity of diabetic retinopathy. At this stage, the growth factor triggers the retina to form new blood vessels. These new blood vessels are fragile and are likely to leak and bleed. This lead to the contraction of scar tissues which causes retinal detachment. Retinal detachment is a process of ripping away of the retina from the underlying tissue. The retinal detachment can cause permanent vision loss.
Reference: https://ieeexplore.ieee.org/document/8721315
Misc
Regional merging can be intergated in the data loader pipeline of CNN itself, but it will be taking time as it may repeat the merging on image twice or more. Rather merge the retinal segmenation on to image, so we can elimate the UNet part in the CNN pipeline
TODO
Retrain CNN to improve accuracy
Reference:
- https://ieeexplore.ieee.org/document/8721315
- https://www.degruyter.com/document/doi/10.1515/bmt-2020-0089/html
- https://github.com/DeepTrial/Retina-VesselNet
- https://www.hindawi.com/journals/jhe/2017/4897258/
- https://www.researchgate.net/publication/332263231_Generation_of_binary_mask_of_retinal_fundus_image_using_bimodal_masking
- https://www.kaggle.com/c/diabetic-retinopathy-detection/data