Short IV infusion

[cohanlon2]

Hi Andrew,

I am having trouble implementing a short IV infusion. The rationale for wanting to do this being that an IV ‘bolus’ is actually given over a period of time e.g. 3 minutes.
Using the code you posted on 11 Jul 2017, with low values of TINF = 0.5, the model prediction graph seems to miss some of the subsequent doses.
If TINF = 1, there doesn’t seem to be this problem.
The issue seems to depend on the DOSE/TINF value (and therefore the amount “In”).

Do you have any suggestions getting this short IV infusion to work?

Best,
Conor

Originally posted by @cohanlon2 in #11 (comment)

[Andrew Hooker]

Duplicate of #11 (comment)