ameeshagireesh / noncoding-rna-breastcancer

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Database on Non-Coding RNAs In Breast Cancer

Overview of Methodology:

  • At present, there exists no unique noncoding RNA databases on breast cancer, all the information that we get regarding them are from public biomedical databases such as NCBI.

  • Call API from a server code, and let the server code parse the response.

  • Decipher the response to create our own table that will be displayed on webpage.

  • Information will be placed in our database, which will be updated regularly, because API will be called on a regular basis (such as every hour, every day, etc.) to see if there are any changes.
    https://www.ncbi.nlm.nih.gov/home/develop/api/ https://www.cancergenomeinterpreter.org/rest_api

  • Tech stack -

    • Frontend - React.js
    • Backend - Node.js with GraphQL (for queries) and MongoDB (for DB).
  • A review article based on specific noncoding RNAs in Breast Cancer will be written.

References:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316884/ https://www.ncbi.nlm.nih.gov/books/NBK99561/ https://www.frontiersin.org/articles/10.3389/fonc.2019.01325/full https://www.frontiersin.org/articles/10.3389/fgene.2020.00680/full https://journals.sagepub.com/doi/full/10.1177/1533033819843889 https://www.tandfonline.com/doi/full/10.1080/15476286.2019.1592072 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858561/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354927/

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