Nextomics / NextDenovo

Fast and accurate de novo assembler for long reads

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For low base quality of sequences

YouxinZhao opened this issue · comments

I am using nextDenovo to assamble genome with ONT reads.
The long reads usually have low base quality.
And I wonder how these sequences will be handled in Nextdenove? Discard or correct?
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Nextdenovo discards reads with low mapping coverage or clips regions of low mapping coverage in reads, and low-quality reads generally have lower mapping coverage.