FRED-2 / OptiType

Precision HLA typing from next-generation sequencing data

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HLA class II prediction

SNRNS opened this issue · comments

Hello again,

The OptiType paper says that "[OptiType] can be easily adapted to predict genotypes for loci other than HLA-I such as HLA-II". I was wondering if it's just a matter of changing some parameters in OptiTypePipeline.py or is something different. In any case, I am very interested in predicting HLA class II, so I was wondering how achievable this would be.

Best,
Alejandro

Hi,
I have managed to install and run Optitype perfectly and I am wondering if there is a way to include HLA-II alleles. I would be really interested in the feature and I would like to know how to do it. I like how fast optitype runs and kudos to that.