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EDePasquale / DoubletDecon

A tool for removing doublets from single-cell RNA-seq data

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Improved_Seurat_Pre_Process: Error in asMethod(object)

jraymond105 opened this issue · comments

commented

When I run the following command on my Seurat object (dataset):

Improved_Seurat_Pre_Process(dataset, num_genes=50, write_files=FALSE)

I get the following:

Error in asMethod(object) :
Cholmod error 'problem too large' at file ../Core/cholmod_dense.c, line 105

Edit: it looks like it is because the dataset I am working with is too large (~200,000 cells)